HCID 131731764, compound → HCID 131731763, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of Example 125A (500 mg, 1.88 mmol) in acetonitrile (8 mL) was added a solution of gold (III) chloride (56.9 mg, 0.188 mmol) in acetonitrile (2 mL). The reaction mixture was stirred at 50° C. for 16 hours and then concentrated. The residue was purified by column chromatography using an Analogix® Intelliflash280™ (SiO2, 0-50% of MeOH/EtOAc (1:10) in hexanes) to obtain 400 mg (80%) the title compound. MS (ESI+) M/Z 267 [M+H]+.

Provenance & Evidence