3-Methyl-4-pyridinamine → HCID 11545718, compound

HRID 2404497Notes

Reaction equation

HRID 2404497 reaction equation
FC1C=C[CH:5]=[C:4](F)[C:3]=1[NH:9][C:10]([C:12]1[S:13][C:14]([C:17]2[CH:22]=[C:21]([C:23]([F:26])([F:25])[F:24])[CH:20]=[CH:19][C:18]=2[Cl:27])=[CH:15][CH:16]=1)=[O:11].[CH3:28][C:29]1[CH:30]=[N:31]C=CC=1N.FC1C=CC=C(F)C=1N>>[CH3:28][C:29]1[CH:30]=[N:31][CH:5]=[CH:4][C:3]=1[NH:9][C:10]([C:12]1[S:13][C:14]([C:17]2[CH:22]=[C:21]([C:23]([F:25])([F:24])[F:26])[CH:20]=[CH:19][C:18]=2[Cl:27])=[CH:15][CH:16]=1)=[O:11]

Participants

4

Reactant 3

HCID 748113-Methyl-4-pyridinamineHCID 796472,6-DifluoroanilineHCID 11553502HCID 11553502, compound

Product 1

HCID 11545718HCID 11545718, compound

Procedure

Compound 2 was synthesized in an analogous fashion as described for Compound 1 except that 3-methyl-4 amino pyridine was used in step 2 instead of 2,6-difluoroaniline.

Sources & evidence

ORD record
ord-a55dd885bc24413e8e8ab70bec0cc2c3
Source dataset
uspto-grants-2014_08
Patent number
US08802721B2

Reaction notes

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