HCID 11553502, compound → HCID 11653926, compound

HRID 2404498Notes

Reaction equation

HRID 2404498 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[NH:9][C:10]([C:12]1[S:13][C:14](C2C=C(C(F)(F)F)C=CC=2Cl)=[CH:15][CH:16]=1)=[O:11].[CH3:28][O:29][C:30](=[O:39])[C:31]1[CH:36]=[CH:35][C:34]([CH3:37])=[C:33](I)[CH:32]=1>>[CH3:28][O:29][C:30](=[O:39])[C:31]1[CH:36]=[CH:35][C:34]([CH3:37])=[C:33]([C:14]2[S:13][C:12]([C:10](=[O:11])[NH:9][C:3]3[C:2]([F:1])=[CH:7][CH:6]=[CH:5][C:4]=3[F:8])=[CH:16][CH:15]=2)[CH:32]=1

Participants

3

Reactant 2

HCID 11553502HCID 11553502, compoundHCID 13614033Methyl 3-iodo-4-methylbenzoate

Product 1

HCID 11653926HCID 11653926, compound

Procedure

Compound 3 was synthesized in an analogous fashion as described for Compound 1 except that 3-iodo-4-methyl-benzoic acid methyl ester was used instead of 1-chloro-2-iodo-4-trifluoromethyl-benzene in step 1.

Sources & evidence

ORD record
ord-3ec7ce49ab1d45109e815ee16a0c7833
Source dataset
uspto-grants-2014_08
Patent number
US08802721B2

Reaction notes

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