HuagongsheHuagongshe Chemistry Print Report · For research reference only
[2-Methyl-5-(1,3-oxazol-2-yl)phenyl]boronic acid → 2,6-Difluoro-N-[5-(2-methyl-5-oxazol-2-yl-phenyl)-thiophen-2-yl]-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [2-Methyl-5-(1,3-oxazol-2-yl)phenyl]boronic acid | HCID 53414650 | — |
| Reactant | 2,6-Difluoro-N-[5-(3-trifluoromethyl-phenyl)-thiophen-2-yl]benzamide | HCID 58703377 | — |
| Product | 2,6-Difluoro-N-[5-(2-methyl-5-oxazol-2-yl-phenyl)-thiophen-2-yl]-benzamide | HCID 11639836 | — |
Reaction Steps
Compound 119 was synthesized in an analogous fashion as described for Compound 117 except that 5-(oxazol-2-yl)-2-methylbenzeneboronic acid was used instead of 3-trifluoromethylbenzeneboronic acid in the final step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08802721B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-63d3c4cabdd14c0c9938924bb24f7a48 |
| Source note | uspto-grants-2014_08 |