1H-Pyrrolo(2,3-b)pyridine → HCID 178524353, compound

Participants

Reaction Steps

To a solution of 7-azaindole (Int-5, 23.6 g, 200 mmol) in DME/heptane (1:2, 300 mL) was added 3-chloroperoxybenzoic acid (85 wt %, 44.7 g, 220 mmol) portion-wise. The slurry was stirred at room temperature for 3 h. The precipitate was collected by filtration and washed with heptane (100 mL). After dried, 51.9 g of 7-azaindole N-oxide 3-chlorobenzoate was obtained (51.9 g, 89%). mp 140-143° C.

Provenance & Evidence