反应详情

To 1-(2-methoxyl-5-chlorophenyl)-3-{1-[1-(t-butyloxycarbonyl)-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl]-1H-indol-4-yl}urea (500 mg, 0.92 mmol) was added hydrogen chloride methanol solution (25%), and the resulting mixture was stirred overnight, then concentrated to give the product 1-(2-Methoxyl-5-chlorophenyl)-3-[1-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-1H-indol-4-yl]urea hydrochloride (412 mg, 93%).

1. concentrationconcentrated