Formamide → HCID 178518065, compound

HRID 2404948Notes

Reaction equation

HRID 2404948 reaction equation
C([O:3][C:4]([C:6]1[C:7]2[CH:15]=[CH:14][CH:13]=[CH:12][C:8]=2[S:9][C:10]=1[NH2:11])=O)C.[CH:16]([NH2:18])=O>>[N:11]1[C:10]2[S:9][C:8]3[CH:12]=[CH:13][CH:14]=[CH:15][C:7]=3[C:6]=2[C:4]([OH:3])=[N:18][CH:16]=1

Participants

3

Reactant 2

HCID 713FormamideHCID 699464Ethyl 2-amino-1-benzothiophene-3-carboxylate

Product 1

HCID 178518065HCID 178518065, compound

Procedure

The solution of 10 millimol IX in 15 milliliter milliliter formamide was stirred at 100° C. for 3 hours then cooled down to room temperature. The reaction mixture was poured onto crushed ice with continuous stirring then collected by filtration. The product was washed with water and n-hexane, then dried.

Workup

  1. additionThe reaction mixture was poured
  2. customonto crushed ice
  3. filtrationthen collected by filtration
  4. washThe product was washed with water and n-hexane
  5. customdried

Sources & evidence

ORD record
ord-fcd1f227558b4307b108c50fdc9d3f9d
Source dataset
uspto-grants-2014_08
Patent number
US08802849B2

Reaction notes

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