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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 240506Erstellt: 25. Oktober 2026

2-(2-Fluorophenyl)ethylamine → (3aR,6aS)-tert-butyl 5-(5-(2-fluorophenethylcarbamoyl)pyridin-3-yl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate

https://huagongshe.com/reaction/240506

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-(2-Fluorophenyl)ethylamineHCID 643357—
Edukt5-((3aR,6aS)-5-(tert-butoxycarbonyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)nicotinic AcidHCID 67265367—
Produkt(3aR,6aS)-tert-butyl 5-(5-(2-fluorophenethylcarbamoyl)pyridin-3-yl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylateHCID 67265607—

Reaktionsschritte

The product from Example 33B and 2-(2-fluorophenyl)ethanamine were processed as described in Example 33C to provide the title compound. MS (ESI) m/z 455 (M+H)+.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08648084B2
Quelldatensatzuspto-grants-2014_02
ORD IDord-46f9a5b19eb64faea5d5380019cf6ae7
Quellennotizuspto-grants-2014_02