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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 240516Generated: October 25, 2026

3-(Propan-2-yloxy)aniline → (3aR,6aS)-tert-butyl 5-(5-(3-isopropoxyphenylcarbamoyl)pyridin-3-yl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate

https://huagongshe.com/reaction/240516

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Propan-2-yloxy)anilineHCID 573220—
Reactant5-((3aR,6aS)-5-(tert-butoxycarbonyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)nicotinic AcidHCID 67265367—
Product(3aR,6aS)-tert-butyl 5-(5-(3-isopropoxyphenylcarbamoyl)pyridin-3-yl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylateHCID 66917056—

Reaction Steps

The product from Example 33B and 3-isopropoxyaniline were processed as described in Example 33C to provide the title compound. MS (APCI) m/z 467 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08648084B2
Source datasetuspto-grants-2014_02
ORD IDord-c8e1718036114460a57888e1a544f505
Source noteuspto-grants-2014_02