3,4-Dichlorophenethylamine → HCID 67265721, compound

HRID 240523Notes

Reaction equation

HRID 240523 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:12][C@H:11]2[CH2:13][N:14]([C:16]3[CH:17]=[N:18][CH:19]=[C:20]([CH:24]=3)[C:21]([OH:23])=O)[CH2:15][C@H:10]2[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[Cl:25][C:26]1[CH:27]=[C:28]([CH:32]=[CH:33][C:34]=1[Cl:35])[CH2:29][CH2:30][NH2:31]>>[Cl:25][C:26]1[CH:27]=[C:28]([CH:32]=[CH:33][C:34]=1[Cl:35])[CH2:29][CH2:30][NH:31][C:21]([C:20]1[CH:24]=[C:16]([N:14]2[CH2:13][C@@H:11]3[CH2:12][N:8]([C:6]([O:5][C:1]([CH3:3])([CH3:4])[CH3:2])=[O:7])[CH2:9][C@@H:10]3[CH2:15]2)[CH:17]=[N:18][CH:19]=1)=[O:23]

Participants

3

Reactant 2

HCID 2179583,4-DichlorophenethylamineHCID 672653675-((3aR,6aS)-5-(tert-butoxycarbonyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)nicotinic Acid

Product 1

HCID 67265721HCID 67265721, compound

Procedure

The product from Example 33B and 3,4-dichlorophenethylamine were processed as described in Example 33C to provide the title compound. MS (APCI) m/z 505 (M+H)+.

Sources & evidence

ORD record
ord-405cf337eb0445df976e7a0db2d93d61
Source dataset
uspto-grants-2014_02
Patent number
US08648084B2

Reaction notes

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