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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2405271Generated: October 30, 2026

methyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate hydrochloride → 2-[4-Methoxy-3-(2-methyl-benzoyl)-benzoylamino]-indane-2-carboxylic acid

https://huagongshe.com/reaction/2405271

Reaction equation

Participants

RoleNameHCIDCharge
Reactantmethyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate hydrochlorideHCID 45074056—
Reactant4-Methoxy-3-(2-methyl-benzoyl)-benzoic acid methyl esterHCID 67076629—
Product2-[4-Methoxy-3-(2-methyl-benzoyl)-benzoylamino]-indane-2-carboxylic acidHCID 67076464—

Reaction Steps

The compound of step 1 was hydrolyzed in analogy to example 2 and the obtained acid reacted with 2-amino-indane-2-carboxylic acid methyl ester hydrochloride in analogy to step 2 of example 13. The obtained ester was hydrolyzed in analogy to example 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08802720B2
Source datasetuspto-grants-2014_08
ORD IDord-cbf1331a9bab437f9cb507afd879b9b0
Source noteuspto-grants-2014_08