HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylbenzeneethanol → 2-[4-Benzyloxy-3-(2-m-tolyl-ethoxy)-benzoylamino]-indane-2-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylbenzeneethanol | HCID 74648 | — |
| Reactant | Ethyl 4-(benzyloxy)-3-hydroxybenzoate | HCID 11311797 | — |
| Reactant | Methyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate | HCID 45074057 | — |
| Product | 2-[4-Benzyloxy-3-(2-m-tolyl-ethoxy)-benzoylamino]-indane-2-carboxylic acid methyl ester | HCID 67076713 | — |
Reaction Steps
The compound of step 2 was reacted with 2-m-tolyl-ethanol in analogy to step 1 of example 1, and the obtained ester was hydrolyzed in analogy to example 2. The obtained carboxylic acid was reacted with 2-amino-indane-2-carboxylic acid methyl ester in analogy to step 2 of example 13.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08802720B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-e6c6a1cf6bca40afa629da7236413594 |
| Source note | uspto-grants-2014_08 |