Dimethylformamide → HCID 14415981, compound

Participants

Reaction Conditions

Reaction Steps

A flask was charged with 5.21 g of benzo[g]chrysene and 50 mL of N,N-dimethylformamide. An N,N-dimethylformamide (10 mL) solution of 4.00 g of N-bromosuccinimide was added to the mixture. The mixture was stirred at 80° C. for 8 hours. After cooling the mixture to room temperature, the reaction solution was poured into 200 mL of water. A solid that precipitated by this operation was collected by filtration, and washed with water and methanol. The resulting solid was purified by silica gel column chromatography to obtain 5.87 g of the target 10-bromobenzo[g]chrysene (yield: 88%).

Provenance & Evidence