참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Cesium carbonate | HCID 10796 | — |
| 반응물 | Benzene, 1-fluoro-2-methyl-4-nitro- | HCID 68001 | — |
| 반응물 | 4-Amino-3-Nitrophenol | HCID 3758882 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 4-(2-Methyl-4-nitrophenoxy)-2-nitrobenzenamine | HCID 86650895 | 87.2% |
반응 단계
To a solution of 1-fluoro-2-methyl-4-nitrobenzene (2.02 g, 13.0 mmol) and 4-amino-3-nitrophenol (2.22 g, 14.4 mmol) in DMF (20 mL) was added cesium carbonate (5.28 g, 16.2 mmol). After heating to 60° C. for 10 hours, the mixture was diluted with water (100 mL) and filtered. The precipitate was washed with water and air-dried to provide the product (3.28 g, 87%) as dark solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08648087B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_02 |
|---|
| ORD ID | ord-e9d0a5f760c24f62b24b9838c724eeb4 |
|---|
| 출처 메모 | uspto-grants-2014_02 |
|---|
