1,4-Benzenediol, 2-nitro- → Aminohydroquinone

HRID 240574Notes

Reaction equation

HRID 240574 reaction equation
[N+:1]([C:4]1[CH:9]=[C:8]([OH:10])[CH:7]=[CH:6][C:5]=1[OH:11])([O-])=O.[H][H]>C(O)C.[Pd]>[NH2:1][C:4]1[CH:9]=[C:8]([OH:10])[CH:7]=[CH:6][C:5]=1[OH:11]

Participants

5

Reactant 2

HCID 43139181,4-Benzenediol, 2-nitro-HCID 178418361HCID 178418361, compound

Product 1

HCID 3017497Aminohydroquinone

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

To a solution of 2-nitrobenzene-1,4-diol (3.00 g, 19.34 mmol) in ethanol (100 mL) was added 10% palladium on carbon (0.600 g, 0.564 mmol). After shaking under 40 psi of hydrogen for 2 hours, the mixture was filtered and the filtrated was concentrated under reduced pressure to provide the product as solid.

Workup

  1. filtrationthe mixture was filtered
  2. concentrationthe filtrated was concentrated under reduced pressure

Sources & evidence

ORD record
ord-e94f863a59724574881cc682a772c620
Source dataset
uspto-grants-2014_02
Patent number
US08648087B2

Reaction notes

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