HCID 178418361, compound → HCID 178431651, compound

Participants

Reaction Steps

3a-[(R)-5-(4-bromobenzyl)-6,6-dimethyl-4,4-dioxo-5,6-dihydro-4H-4lambda6-[1,4,3]oxathiazin-2-ylamino]hexahydro-2,5-methanopentalene-2-carboxamide (80 mg) was dissolved in ethanol and stirred in a hydrogen atmosphere (5 bar) in the presence of palladium on charcoal (10%) for 30 min. The solution was filtered and concentrated. Purification was effected by preparative HPLC. This gave the product (33 mg) with a molecular weight of 431.5 g/mol (C22H29N3O4S), MS (ESI): (M+H+) 432.5 g/mol.

Provenance & Evidence