HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(2-Methyl-4-nitrophenoxy)benzo[d]oxazole → 4-(Benzo[d]oxazol-5-yloxy)-3-methylbenzenamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(2-Methyl-4-nitrophenoxy)benzo[d]oxazole | HCID 66936930 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(Benzo[d]oxazol-5-yloxy)-3-methylbenzenamine | HCID 66937288 | 55.1% |
Reaction Steps
To a solution of 5-(2-methyl-4-nitrophenoxy)benzo[d]oxazole (1.65 g, 6.12 mmol) in ethanol was added Pd/C (0.130 g, 0.122 mmol). After stirring under hydrogen atmosphere for 16 hours, the mixture was filtered and the filtrate was concentrated to provide the product (0.81 g, 55%) as yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648087B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-9c231314464c4c82a9eae3012e9cf287 |
| Source note | uspto-grants-2014_02 |