4-(N-Boc-amino)piperidine → HCID 57899177, compound

HRID 2405964Notes

Reaction equation

HRID 2405964 reaction equation
Cl[C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[NH:4][C:5](=[O:11])[NH:6]2.[C:12]([O:16][C:17](=[O:25])[NH:18][CH:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1)([CH3:15])([CH3:14])[CH3:13]>>[C:12]([O:16][C:17](=[O:25])[NH:18][CH:19]1[CH2:24][CH2:23][N:22]([C:2]2[N:10]=[CH:9][N:8]=[C:7]3[C:3]=2[NH:4][C:5](=[O:11])[NH:6]3)[CH2:21][CH2:20]1)([CH3:15])([CH3:13])[CH3:14]

Participants

3

Reactant 2

HCID 7238334-(N-Boc-amino)piperidineHCID 576592036-CHLORO-7H-PURIN-8(9H)-ONE

Product 1

HCID 57899177HCID 57899177, compound

Procedure

By reacting 6-chloro-7,9-dihydro-purin-8-one with piperidin-4-yl-carbamic acid tert-butyl ester according to the method of Example 4A, the title compound was obtained. LC/MS: (LCT) Rt 5.68 [M+H]+ 335.

Sources & evidence

ORD record
ord-ee72989e6b4945488e14e01ea52d3bb9
Source dataset
uspto-grants-2014_08
Patent number
US08809336B2

Reaction notes

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