Succinic Acid → HCID 178457292, compound

Participants

Reaction Conditions

Reaction Steps

0.535 g of 3-(3-{2-[(E)-3,5-Diamino-6-chloro-pyrazine-2-carbonylimino]-1,3,8-triaza-spiro[4.5]decane-8-carbonyl}-benzenesulfonylamino)-propionic acid dipropylcarbamoylmethyl ester (may be prepared as in Preparation 1) and 0.12 g succinic acid were dissolved in 7.27 g methyl ethyl ketone at 60° C. in a magnetically stirred glass vial. The solution was cooled to 20° C. and then stirred at this temperature overnight. The resulting suspension was filtered.

Provenance & Evidence