4-Fluoro-3-(trifluoromethyl)benzene-1-sulfonamide → HCID 25140033, compound

HRID 2406212Notes

Reaction equation

HRID 2406212 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH2:11])(=[O:10])=[O:9])=[CH:4][C:3]=1[C:12]([F:15])([F:14])[F:13].[CH3:16][N:17]([CH3:30])[CH2:18][CH2:19][C@@H:20]([NH2:29])[CH2:21][S:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[CH3:30][N:17]([CH3:16])[CH2:18][CH2:19][C@@H:20]([NH:29][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH2:11])(=[O:10])=[O:9])=[CH:4][C:3]=1[C:12]([F:15])([F:14])[F:13])[CH2:21][S:22][C:23]1[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 283069314-Fluoro-3-(trifluoromethyl)benzene-1-sulfonamideHCID 58080194HCID 58080194, compound

Product 1

HCID 25140033HCID 25140033, compound

Procedure

The title compound was prepared from 4-fluoro-3-(trifluoromethyl)-benzenesulfonamide and (R)—N1,N1-dimethyl-4-phenylsulfanyl-butane-1,3-diamine using the procedure described for Intermediate 4.

Sources & evidence

ORD record
ord-05ee3c5127a64b1c9a04f4b2454d47a4
Source dataset
uspto-grants-2014_08
Patent number
US08809352B2

Reaction notes

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