3-Cyano-4-fluorobenzene-1-sulfonamide → HCID 25139033, compound

HRID 2406213Notes

Reaction equation

HRID 2406213 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH2:11])(=[O:10])=[O:9])=[CH:4][C:3]=1[C:12]#[N:13].[CH3:14][N:15]([CH3:28])[CH2:16][CH2:17][C@@H:18]([NH2:27])[CH2:19][S:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[C:12]([C:3]1[CH:4]=[C:5]([S:8]([NH2:11])(=[O:10])=[O:9])[CH:6]=[CH:7][C:2]=1[NH:27][C@H:18]([CH2:17][CH2:16][N:15]([CH3:14])[CH3:28])[CH2:19][S:20][C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)#[N:13]

Participants

3

Reactant 2

HCID 251398973-Cyano-4-fluorobenzene-1-sulfonamideHCID 58080194HCID 58080194, compound

Product 1

HCID 25139033HCID 25139033, compound

Procedure

The title compound was prepared from 4-fluoro-3-(cyano)benzenesulfonamide and (R)—N1,N1-dimethyl-4-phenylsulfanyl-butane-1,3-diamine using the procedure described for Intermediate 4.

Sources & evidence

ORD record
ord-0a9732043eb644ba8e543c41d284f6c1
Source dataset
uspto-grants-2014_08
Patent number
US08809352B2

Reaction notes

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