3,4,5-Trifluorobenzene-1-sulfonamide → HCID 67980643, compound

HRID 2406214Notes

Reaction equation

HRID 2406214 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([S:10]([NH2:13])(=[O:12])=[O:11])[CH:5]=[C:6]([F:9])[C:7]=1F.[CH3:14][N:15]([CH3:28])[CH2:16][CH2:17][C@@H:18]([NH2:27])[CH2:19][S:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[CH3:28][N:15]([CH3:14])[CH2:16][CH2:17][C@@H:18]([NH:27][C:7]1[C:6]([F:9])=[CH:5][C:4]([S:10]([NH2:13])(=[O:11])=[O:12])=[CH:3][C:2]=1[F:1])[CH2:19][S:20][C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1

Participants

3

Reactant 2

HCID 283069343,4,5-Trifluorobenzene-1-sulfonamideHCID 58080194HCID 58080194, compound

Product 1

HCID 67980643HCID 67980643, compound

Procedure

The title compound was prepared from 3,4,5-trifluorobenzenesulfonamide and (R)—N1,N1-dimethyl-4-phenylsulfanyl-butane-1,3-diamine using the procedure described for Intermediate 4.

Sources & evidence

ORD record
ord-74adfe5dec2a490f91548b547ae11098
Source dataset
uspto-grants-2014_08
Patent number
US08809352B2

Reaction notes

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