戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 240625作成日：2026年10月25日

Methyl 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylate → 4-[2-((S)-1-tert-Butoxycarbonyl-piperidin-3-yloxy)-pyridin-3-ylamino]-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester

https://huagongshe.com/reaction/240625

反応式

関与物質

役割名称HCID仕込み量
反応物Methyl 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylateHCID 2759834—
反応物(S)-tert-butyl 3-(3-aminopyridin-2-yloxy)piperidine-1-carboxylateHCID 58413073—
生成物4-[2-((S)-1-tert-Butoxycarbonyl-piperidin-3-yloxy)-pyridin-3-ylamino]-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl esterHCID 58413070—

反応手順

Prepared analogously to example 1.1. from 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester and (S)-tert-butyl 3-(3-aminopyridin-2-yloxy)piperidine-1-carboxylate (Intermediate X)

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08648068B2
出典データセットuspto-grants-2014_02
ORD IDord-63ab46e01b204ad3b6e786949af8076f
出典メモuspto-grants-2014_02