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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2406318Generated: November 3, 2026

(2-Fluoro-3-methoxy-4-nitrophenyl)(morpholino)methanone → (4-Amino-2-fluoro-3-methoxyphenyl)(morpholino)methanone

https://huagongshe.com/reaction/2406318

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Fluoro-3-methoxy-4-nitrophenyl)(morpholino)methanoneHCID 70099135—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product(4-Amino-2-fluoro-3-methoxyphenyl)(morpholino)methanoneHCID 58539264—

Reaction Steps

A suspension of (2-fluoro-3-methoxy-4-nitrophenyl)(morpholino)methanone (0.20 g) and palladium on carbon (0.1 g, 10 wt %) in ethanol was stirred under hydrogen for 18 hours. The reaction then filtered through celite and concentrated to give (4-amino-2-fluoro-3-methoxyphenyl)(morpholino)methanone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08809331B2
Source datasetuspto-grants-2014_08
ORD IDord-306e3e29bca1499ba6737e5188b48b54
Source noteuspto-grants-2014_08