HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-(trifluoromethyl)pyridine → HCID 86701207, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-(trifluoromethyl)pyridine | HCID 92342 | — |
| Reactant | 5-(1-Methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-dispiro[2,3-dihydrofuro[2,3-c]pyridine-2,1'-cyclobutane-3',4''-piperidine] | HCID 86701204 | — |
| Product | HCID 86701207 | HCID 86701207 | — |
Reaction Steps
The title compound is prepared from 5-(1-methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-dispiro[2,3-dihydrofuro[2,3-c]pyridine-2,1′-cyclobutane-3′,4″-piperidine] (HCl salt) and 2-chloro-5-trifluoromethyl-pyridine following a procedure analogous to that described for Example 4. LC (method 1): tR=1.09 min; Mass spectrum (ESI+): m/z=535 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08809361B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-2b24c41645264829adfa77fca2ee305f |
| Source note | uspto-grants-2014_08 |