反应详情

The title compound is prepared from 5-chloro-1″-tert-butoxycarbonyl-dispiro[2,3-dihydrofuro[2,3-c]pyridine-2,1′-cyclobutane-3′,4″-piperidine] and 6-methylsulfonyl-pyridine-3-boronic acid pinacol ester following a procedure analogous to that described for Example 1; the reaction is conducted in a microwave oven at 140° C. LC (method 3): tR=1.07 min; Mass spectrum (ESI+): m/z=486 [M+H]+.

1. customthe reaction is conducted in a microwave oven at 140° C