反应详情

The title compound is prepared from 5-(1-methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-dispiro[2,3-dihydrofuro[2,3-c]pyridine-2,1′-cyclobutane-3′,4″-piperidine] (HCl salt) and 2-chloro-5-cyclopropyl-pyrimidine following a procedure analogous to that described for Example 15. LC (method 3): tR=0.85 min; Mass spectrum (ESI+): m/z=508 [M+H]+.