HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-trifluoromethyl-(1,3,4)thiadiazole → HCID 86701214, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-trifluoromethyl-(1,3,4)thiadiazole | HCID 13246789 | — |
| Reactant | 5-(1-Methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-dispiro[2,3-dihydrofuro[2,3-c]pyridine-2,1'-cyclobutane-3',4''-piperidine] | HCID 86701204 | — |
| Product | HCID 86701214 | HCID 86701214 | — |
Reaction Steps
The title compound is prepared from 5-(1-methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-dispiro[2,3-dihydrofuro[2,3-c]pyridine-2,1′-cyclobutane-3′,4″-piperidine] (HCl salt) and 2-chloro-5-trifluoromethyl-[1,3,4]thiadiazole following a procedure analogous to that described for Example 15. LC (method 3): tR=0.93 min; Mass spectrum (ESI+): m/z=542 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08809361B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-6308e5ee4f78466696fe38a35d7106f9 |
| Source note | uspto-grants-2014_08 |