反应详情

The title compound is prepared from N-hydroxy-butyramidine and 1″-cyano-5-(1-methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-dispiro[2,3-dihydrofuro[2,3-c]pyridine-2,1′-cyclobutane-3′,4″-piperidine] following a procedure analogous to that described for Example 23. LC (method 3): tR=0.91 min; Mass spectrum (ESI+): m/z=500 [M+H]+.