HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 58413204, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | HCID 58413158 | HCID 58413158 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | HCID 58413204 | HCID 58413204 | — |
Reaction Steps
Prepared analogously to example 96.4 from 4-[2-((3S,5S)-1-tert-butoxycarbonyl-5-hydroxymethyl-pyrrolidin-3-yloxy)-4-fluoro-phenylamino]-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid amide and acetic anhydride. The acetic anhydride was added at 0° C. and a catalytic amount of DMAP was used.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648068B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-b88a515e229c4177a47d6db4d554febf |
| Source note | uspto-grants-2014_02 |