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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2406518Generated: November 4, 2026

{(S)-6-[(R)-4-bromo-5-trifluoromethyl-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester → HCID 86700783, compound

https://huagongshe.com/reaction/2406518

Reaction equation

Participants

RoleNameHCIDCharge
Reactant{(S)-6-[(R)-4-bromo-5-trifluoromethyl-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl esterHCID 86700774—
ReactantHCID 178419772HCID 178419772—
ProductHCID 86700783HCID 86700783—

Reaction Steps

The title compound is prepared from {(S)-6-[(R)-4-bromo-5-trifluoromethyl-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester and benzylzinc bromide following a procedure analogous to that described in Step 6 of Intermediate 1. LC (method 3): tR=0.94 min; Mass spectrum (ESI+): m/z=505 [M+Na]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08809376B2
Source datasetuspto-grants-2014_08
ORD IDord-5d13cc59d6ff4bc48964f5f867bbe0af
Source noteuspto-grants-2014_08