HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethylaminoethyl chloride hydrochloride → HCID 23146084, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethylaminoethyl chloride hydrochloride | HCID 11636816 | — |
| Reactant | 1-(4-(2-(Diethylamino)ethoxy)phenyl)butan-1-one | HCID 66822369 | — |
| Product | HCID 23146084 | HCID 23146084 | 81% |
Reaction Steps
The title compound was prepared using a similar procedure as described for the preparation of 21 except that 2-(dimethylamino)ethyl chloride hydrochloride was used instead of 2-(diethylamino)ethyl chloride hydrochloride. This produced a crude oil, which was purified by flash silica gel column chromatography (gradient elution from 1:1 hexanes/ethyl acetate to ethyl acetate) to give 22 (580 mg, 81%) as a light yellow oil: MS (ES+) m/z 236.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08809377B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-1a56eee0f2914a68a2c10b73e227ec5f |
| Source note | uspto-grants-2014_08 |