HCID 23146084, compound → 1-(4-(2-(Dimethylamino)ethoxy)phenyl)butan-1-amine

HRID 2406577Notes

Reaction equation

HRID 2406577 reaction equation
[CH2:1]([N:3]([CH2:18]C)[CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH:13]([NH2:17])[CH2:14][CH2:15][CH3:16])=[CH:9][CH:8]=1)C.CN(C)CCOC1C=CC(C(=O)CCC)=CC=1>>[CH3:18][N:3]([CH3:1])[CH2:4][CH2:5][O:6][C:7]1[CH:8]=[CH:9][C:10]([CH:13]([NH2:17])[CH2:14][CH2:15][CH3:16])=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 23146084HCID 23146084, compoundHCID 66822143HCID 66822143, compound

Product 1

HCID 668222551-(4-(2-(Dimethylamino)ethoxy)phenyl)butan-1-amineYield 73%

Procedure

The title compound was prepared by using a similar procedure as described for the preparation of 25 except that 1-(4-(2-(dimethylamino)ethoxy)phenyl)butan-1-one (22) was used instead of 1-(4-(2-(diethylamino)ethoxy)phenyl)butan-1-one (21). This produced crude 26 (410 mg, 73%) as a yellow oil: MS (ES+) m/z 237.1 (M+H)+.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-efba2276936e4dbeba0c17a0186321ed
Source dataset
uspto-grants-2014_08
Patent number
US08809377B2

Reaction notes

Loading…