Hydrochloric Acid → HCID 58413071, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 166 mg (0.92 mmol) 2-[(R)-(tetrahydro-furan-3-yl)oxy]-pyridin-3-ylamine, 364 mg (1.5 mmol) 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester and 39 μl hydrochloric acid (4M in dioxane) and 30 ml dioxane was stirred at 100° C. for 1.5 days. The reaction mixture was concentrated and used for the next synthesis step without further purification.

Provenance & Evidence