反应详情

The title compound was prepared by using a similar procedure as described for the preparation of 33 except that 2-cyano-N-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-butyl)acetamide (30) was used instead of 2-cyano-N-(1-(4-(2-(diethylamino)ethoxy)phenyl)butyl)acetamide (29). This produced the crude product which was purified by flash silica gel column chromatography, eluting with 4:96 methanol/dichloromethane, to give 35 (120 mg, 76%) as a yellow oil: MS (ES+) m/z 471.1 (M+H)+.

1. customThis produced the crude product which