Ammonia → HCID 58413091, compound

HRID 240659Notes

Reaction equation

HRID 240659 reaction equation
[CH3:1][C:2]1[C:10]2[C:9]([NH:11][C:12]3[C:13]([O:18][C@@H:19]4[CH2:23][CH2:22][O:21][CH2:20]4)=[N:14][CH:15]=[CH:16][CH:17]=3)=[N:8][CH:7]=[N:6][C:5]=2[S:4][C:3]=1[C:24]([OH:26])=O.[NH3:27]>>[CH3:1][C:2]1[C:10]2[C:9]([NH:11][C:12]3[C:13]([O:18][C@@H:19]4[CH2:23][CH2:22][O:21][CH2:20]4)=[N:14][CH:15]=[CH:16][CH:17]=3)=[N:8][CH:7]=[N:6][C:5]=2[S:4][C:3]=1[C:24]([NH2:27])=[O:26]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 58413058HCID 58413058, compound

Product 1

HCID 58413091HCID 58413091, compound

Procedure

Prepared analogously to example 10.4 from 5-methyl-4-{2-[(R)-(tetrahydro-furan-3-yl)oxy]-pyridin-3-ylamino}-thieno[2,3-d]pyrimidine-6-carboxylic acid and ammonia.

Sources & evidence

ORD record
ord-eb74433d8eeb427ba4a9c8f8abbef1bf
Source dataset
uspto-grants-2014_02
Patent number
US08648068B2

Reaction notes

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