Methyl 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylate → HCID 68239860, compound

HRID 240660Notes

Reaction equation

HRID 240660 reaction equation
[O:1]1[CH2:5][CH2:4][C@H:3]([O:6][C:7]2[C:12]([NH2:13])=[CH:11][CH:10]=[CH:9][N:8]=2)[CH2:2]1.[CH3:14][O:15][C:16]([C:18]1[S:27][C:21]2[N:22]=[CH:23][N:24]=[C:25](Cl)[C:20]=2[C:19]=1[CH3:28])=[O:17]>>[CH3:14][O:15][C:16]([C:18]1[S:27][C:21]2[N:22]=[CH:23][N:24]=[C:25]([NH:13][C:12]3[C:7]([O:6][C@H:3]4[CH2:4][CH2:5][O:1][CH2:2]4)=[N:8][CH:9]=[CH:10][CH:11]=3)[C:20]=2[C:19]=1[CH3:28])=[O:17]

Participants

3

Reactant 2

HCID 2759834Methyl 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylateHCID 58413131HCID 58413131, compound

Product 1

HCID 68239860HCID 68239860, compound

Procedure

Prepared analogously from 2-[(S)-(tetrahydro-furan-3-yl)oxy]-pyridin-3-ylamine and 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester.

Sources & evidence

ORD record
ord-d0f0904bf8d945f882f05465d988ee14
Source dataset
uspto-grants-2014_02
Patent number
US08648068B2

Reaction notes

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