HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole → 1-Hexyl-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole | HCID 798 | — |
| Reactant | 1-Bromohexane | HCID 8101 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 1-Hexyl-1H-indole | HCID 12715404 | — |
Reaction Steps
To a solution of 1H-indole in DMSO was added KOH at RT and was stirred for 30 minutes. Then to this mixture, 1-bromo-hexane was added and stirred for 3 hours. The reaction was treated with saturated ammonium chloride and ethyl acetate. The product was purified by column chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08809382B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-e2f4ee4111df4e23822596d001102ed1 |
| Source note | uspto-grants-2014_08 |