Ammonium Chloride → HCID 66644093, compound

Participants

Reaction Steps

To a solution of 1-hexyl-1H-indole in methylene chloride at 0° C. was added dimethyl aluminum chloride solution in hexane. The reaction mixture was stirred for 30 minutes. To the above reaction mixture was added 4-chlorocarbonyl-butyric acid methyl ester at 0° C. and the reaction mixture was stirred for 3 hours. The reaction was treated with saturated ammonium chloride and ethyl acetate. The product was purified by column chromatography.

Provenance & Evidence