HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 3-Hexyl-1-methyl-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | 3-Hexyl-1H-indole | HCID 15723575 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-Hexyl-1-methyl-1H-indole | HCID 68747124 | — |
Reaction Steps
To a solution of 3-hexyl-1H-Indole in DMSO was added KOH at RT and was stirred for 30 minutes. Iodomethane was added to the above mixture and stirred for 3 hours. The reaction was treated with saturated ammonium chloride and ethyl acetate. The product was purified by column chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08809382B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-4ceb6b3a387143feae35d74a93679eab |
| Source note | uspto-grants-2014_08 |