2-Hex-1-enyl-1H-indole → HCID 14299246, compound

HRID 2406638Notes

Reaction equation

HRID 2406638 reaction equation
[CH:1]([C:7]1[NH:8][C:9]2[C:14]([CH:15]=1)=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:2][CH2:3][CH2:4][CH2:5][CH3:6].[H][H]>C(O)C.[Pd]>[CH2:1]([C:7]1[NH:8][C:9]2[C:14]([CH:15]=1)=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

5

Reactant 2

HCID 666441492-Hex-1-enyl-1H-indoleHCID 178418361HCID 178418361, compound2×

Product 1

HCID 14299246HCID 14299246, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

2-Hex-1-enyl-1H-indole was dissolved in ethanol and 10% palladium on carbon was added to the solution. The reaction flask was sealed and exposed to hydrogen gas under pressure and was stirred until the hydrogen gas consumption was completely stopped. The reaction mixture was filtered through Celite. The solvent was evaporated to afford the product.

Workup

  1. customThe reaction flask was sealed
  2. filtrationThe reaction mixture was filtered through Celite
  3. customThe solvent was evaporated
  4. customto afford the product

Sources & evidence

ORD record
ord-804316a7650d49c9a1911361162e534d
Source dataset
uspto-grants-2014_08
Patent number
US08809382B2

Reaction notes

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