HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → 5-(2-Hexyl-indol-1-yl)-3(R)-methyl-5-oxo-pentanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | HCID 66643978 | HCID 66643978 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | 5-(2-Hexyl-indol-1-yl)-3(R)-methyl-5-oxo-pentanoic acid | HCID 49804578 | — |
Reaction Steps
To a solution of 5-(2-hexyl-indol-1-yl)-3-methyl-5-oxo-pentanoic acid methyl ester in hexane and buffer was added lipase and was stirred for 24 hours. The reaction mixture was treated with saturated ammonium chloride and ethyl acetate. The product was purified by column chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08809382B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-7f114e99a5ec4d719ff0bf3f58f5fd31 |
| Source note | uspto-grants-2014_08 |