化工社化工社 化学情報印刷レポート · 研究参考用
Ammonium Chloride → 2-Undec-1-enyl-1H-indole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ammonium Chloride | HCID 25517 | — |
| 反応物 | Indole-2-carboxaldehyde | HCID 96389 | — |
| 反応物 | Sodium bis(trimethylsilyl)amide | HCID 2724254 | — |
| 反応物 | Decyltriphenylphosphonium bromide | HCID 3084561 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | 2-Undec-1-enyl-1H-indole | HCID 66644163 | — |
反応手順
To a suspension of decyl-triphenyl-phosphonium bromide in THF was added NaHMDS in THF and the mixture was stirred for 30 minutes and then the solution of 1H-indole-2-carbaldehyde was added to the reaction mixture and stirred for 3 hours. The reaction mixture was treated with saturated ammonium chloride and ethyl acetate. The product was purified by column chromatography.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08809382B2 |
| 出典データセット | uspto-grants-2014_08 |
| ORD ID | ord-2c03dd5d0fdd4d4d9373120cd6e16bb0 |
| 出典メモ | uspto-grants-2014_08 |