2-oct-1-enyl-1H-indole → HCID 10889703, compound

HRID 2406650Notes

Reaction equation

HRID 2406650 reaction equation
[CH:1]([C:9]1[NH:10][C:11]2[C:16]([CH:17]=1)=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[H][H]>C(O)C.[Pd]>[CH2:1]([C:9]1[NH:10][C:11]2[C:16]([CH:17]=1)=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

5

Reactant 2

HCID 687493232-oct-1-enyl-1H-indoleHCID 178418361HCID 178418361, compound2×

Product 1

HCID 10889703HCID 10889703, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

2-Oct-1-enyl-1H-indole was dissolved in ethanol and 10% palladium on carbon was added to the solution. The reaction flask was sealed and exposed to hydrogen gas under pressure and was stirred until the hydrogen gas consumption was completely stopped. The reaction mixture was filtered through celite. The solvent was evaporated to afford the desired product.

Workup

  1. customThe reaction flask was sealed
  2. filtrationThe reaction mixture was filtered through celite
  3. customThe solvent was evaporated

Sources & evidence

ORD record
ord-eae61695ccc84cddbdd97642dbca7eac
Source dataset
uspto-grants-2014_08
Patent number
US08809382B2

Reaction notes

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