HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → HCID 49802588, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 1-Phenethylamine, (+)- | HCID 643189 | — |
| Reactant | HCID 66644104 | HCID 66644104 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 49802588 | HCID 49802588 | — |
Reaction Steps
To the solution of 6-(5-chloro-2-hexyl-1-methyl-1H-indol-3-yl)-4-methyl-2,6-dioxohexanoic acid in methylene chloride was added (R)-1-phenylethanamine followed by the addition of DCC and DMAP and was stirred for 30 minutes. The reaction mixture was treated with sodium bicarbonate and methylene chloride. The product was purified by column chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08809382B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-01bf8e7594cd4f98aac64ed5190d919a |
| Source note | uspto-grants-2014_08 |