6-Chloro-2-hex-1-enyl-1H-indole → 6-chloro-2-hexyl-1H-indole

HRID 2406670Notes

Reaction equation

HRID 2406670 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[C:7]([CH:11]=[CH:12][CH2:13][CH2:14][CH2:15][CH3:16])[NH:8]2)=[CH:4][CH:3]=1.[H][H]>C(O)C.[Pd]>[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[C:7]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[NH:8]2)=[CH:4][CH:3]=1

Participants

5

Reactant 2

HCID 687542166-Chloro-2-hex-1-enyl-1H-indoleHCID 178418361HCID 178418361, compound

Product 1

HCID 105858626-chloro-2-hexyl-1H-indole

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

6-Chloro-2-hex-1-enyl-1H-indole was dissolved in ethanol and 10% palladium on carbon was added to the solution. The reaction flask was sealed and exposed to hydrogen gas under pressure and was stirred for 5 hours. Then the reaction mixture was filtered through Celite. The solvent was evaporated to give 6-Chloro-2-hexyl-1H-indole.

Workup

  1. customThe reaction flask was sealed
  2. filtrationThen the reaction mixture was filtered through Celite
  3. customThe solvent was evaporated

Sources & evidence

ORD record
ord-c417feecba21441195ebcf549ea567fa
Source dataset
uspto-grants-2014_08
Patent number
US08809382B2

Reaction notes

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