Ammonium Hydroxide → HCID 66644054, compound

Participants

Reaction Steps

To the solution of 2-hexyl-quinolin-3-ylamine in hydrobromic acid at -10° C. was added aqueous solution of sodium nitrite followed by bromine and was allowed to warm up to RT. The reaction was continued for 1 day. Next day the reaction mixture was neutralized using aqueous ammonium hydroxide solution and was extracted with ether. The organic layer was washed with aqueous sodium thiosulfate. The product was purified by column chromatography.

Provenance & Evidence