HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 4183387, compound → 5-Methyl-6-(4-morpholinyl)-3-pyridinamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 4183387 | HCID 4183387 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-Methyl-6-(4-morpholinyl)-3-pyridinamine | HCID 59276496 | 90.3% |
Reaction Steps
A methanol (20 ml) solution containing 4-(3-methyl-5-nitropyridin-2-yl)morpholine (67 mg) was prepared and subjected to a hydrogenation reaction (room temperature; 1 bar; flow rate: 1 ml/min; 10% Pd/C) using H-cube™. Then, the solvent was distilled away under reduced pressure, and a purple solid of 5-methyl-6-morpholinopyridin-3-amine (52.4 mg) was thus obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08809371B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-bd0cabfa951a4b3188549f41b294547e |
| Source note | uspto-grants-2014_08 |