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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2406787Generated: November 1, 2026

Prolinol, (R)- → HCID 178470258, compound

https://huagongshe.com/reaction/2406787

Reaction equation

Participants

RoleNameHCIDCharge
ReactantProlinol, (R)-HCID 2724541—
ReactantEthyl 3-hydroxy-5-methoxypicolinateHCID 66962131—
ReactantHCID 178520946HCID 178520946—
ProductHCID 178470258HCID 178470258—

Reaction Steps

The title compound was prepared according to the procedure described in Step 1 of EXAMPLE 29 using ethyl 3-hydroxy-5-methoxypicolinate (EXAMPLE 31 Step 2) and [(2R)-1-{[trans-4-(trifluoromethyl)cyclohexyl]carbonyl}pyrrolidin-2-yl]methanol (EXAMPLE 31 Step 1) instead of 5-chloropyridin-3-ol and (R)-pyrrolidin-2-ylmethanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08809380B2
Source datasetuspto-grants-2014_08
ORD IDord-51c62a1633ba413fb5b3f0bee544ead2
Source noteuspto-grants-2014_08