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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2406791Generated: October 30, 2026

(R)-ethyl 3-((1-(tert-butoxycarbonyl)pyrrolidin-2-yl)methoxy)picolinate → (R)-3-((1-(tert-butoxycarbonyl)pyrrolidin-2-yl)methoxy)picolinic acid

https://huagongshe.com/reaction/2406791

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-ethyl 3-((1-(tert-butoxycarbonyl)pyrrolidin-2-yl)methoxy)picolinateHCID 86666097—
ReactantHCID 178470258HCID 178470258—
Product(R)-3-((1-(tert-butoxycarbonyl)pyrrolidin-2-yl)methoxy)picolinic acidHCID 66962153—

Reaction Steps

The title compound was prepared according to the procedure described in Step 4 of EXAMPLE 31 using (R)-ethyl 3-((1-(tert-butoxycarbonyl)pyrrolidin-2-yl)methoxy)picolinate (EXAMPLE 33 Step 1) in stead of ethyl 5-methoxy-3-(((R)-1-(trans-4-(trifluoromethyl)cyclohexanecarbonyl)pyrrolidin-2-yl)m ethoxy)picolinate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08809380B2
Source datasetuspto-grants-2014_08
ORD IDord-9ddb5cadf38247cfb80f3d175e6779dc
Source noteuspto-grants-2014_08